Nobel Laureates Unveil New Frontiers in Immune Tolerance
Scientists Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi received the 2025 Nobel Prize in Physiology or Medicine for pioneering discoveries in peripheral immune tolerance, vital for combating microbes and preventing autoimmune diseases. Their research spurred new treatments, including for cancer, with the prize ceremony held annually in Sweden and Norway.

In a landmark achievement, scientists Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi have been awarded the 2025 Nobel Prize in Physiology or Medicine. Their groundbreaking work on peripheral immune tolerance has paved the way for novel treatments for conditions such as cancer and autoimmune diseases, the Nobel Assembly announced.
The award highlights the importance of regulating the immune system to effectively combat pathogens while preventing autoimmune responses. The prestigious prize, accompanied by 11 million Swedish crowns and a gold medal, underscores the significance of their contributions to medical science.
Nobel Prizes, established by Alfred Nobel, honor excellence in various fields since 1901, with past recipients from diverse scientific backgrounds. The awards are celebrated in Sweden with grand ceremonies, bringing together laureates and the royal families, to mark humanity's progress in science, literature, and peace.