Nobel Prize 2025: Breakthroughs in Immune System Research

American scientists Mary Brunkow and Fred Ramsdell, alongside Japan's Shimon Sakaguchi, have been awarded the 2025 Nobel Prize in Physiology or Medicine. Their pioneering research on regulatory T cells provides a crucial understanding of peripheral immune tolerance, revealing mechanisms that prevent the immune system from attacking healthy cells.

At a press conference in Osaka, Sakaguchi expressed surprise at this recognition, believing further advancements were necessary for such an honor. He emphasized the potential of their discoveries to make cancer a treatable condition, as demonstrated by ongoing trials in immunotherapy for diseases like inflammatory bowel disease.

The Nobel Assembly's recognition spotlighted the global importance of regulatory T cell research. The ceremony in Sweden underscored the accolades' tradition, with winners receiving 11 million Swedish crowns. The research sparks hope for new treatments against numerous diseases, as scientific and commercial interest in the area continues to grow.

(With inputs from agencies.)