Revolutionizing Bone Medicine: The Secret Role of Sugar Molecules Unveiled

Researchers at the National Institute of Technology, Rourkela discover how sugar-like molecules affect Bone Morphogenetic Protein-2. This revelation promises advanced bone treatment options and better protein-based medicines by controlling protein unfolding and structural stability.


Devdiscourse News Desk | New Delhi | Updated: 13-08-2025 17:02 IST | Created: 13-08-2025 17:02 IST
Revolutionizing Bone Medicine: The Secret Role of Sugar Molecules Unveiled
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Scientists at the National Institute of Technology in Rourkela have made a groundbreaking discovery regarding how natural sugar-like molecules can influence Bone Morphogenetic Protein-2 (BMP-2), a crucial protein in bone formation and repair.

Published in the esteemed journal Biochemistry, the study suggests that sugars known as Glycosaminoglycans (GAGs) can alter BMP-2's behavior, offering potential for advanced bone and cartilage treatments, improved implants, and more efficient protein-based medicines.

The research led by Associate Professor Harekrushna Sahoo, reveals that understanding the precise unfolding of proteins like BMP-2 can have significant implications in medicine, particularly in reducing side effects and enhancing drug delivery.

(With inputs from agencies.)

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