IISER Kolkata's Probiotic Breakthrough: A New Era in Cancer Treatment

A team from IISER Kolkata has developed engineered bacteria that can fight cancer internally. Their ReSET project, targeting T regulatory cells, enhances cancer treatment by reactivating the immune system. Engaging with healthcare experts, the team collaborates on this promising innovation, set to represent India at the 2025 iGEM competition.


Devdiscourse News Desk | Kolkata | Updated: 08-10-2025 10:26 IST | Created: 08-10-2025 10:26 IST
IISER Kolkata's Probiotic Breakthrough: A New Era in Cancer Treatment
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Researchers at the Indian Institute of Science Education and Research (IISER) Kolkata have made significant strides in cancer treatment through engineered probiotics. These 'friendly bacteria' are designed to combat cancer from within, offering an innovative therapeutic solution.

Dubbed the ReSET (Reprogramming the Suppressive Environment of Tumour Microenvironment) project, this initiative addresses the challenge posed by T regulatory cells that often shield cancer from the body's immune defense. By altering these probiotics, the IISER team aims to enhance the effectiveness of existing therapies like immunotherapy and chemotherapy, potentially revolutionizing cancer treatment.

The initiative is not just theoretical; it incorporates insights from oncologists, surgeons, and cancer survivors to ensure a scientifically and socially responsible approach. As the team prepares to showcase their research at the iGEM Grand Jamboree 2025 in Paris, they highlight the potential of India's youth in driving world-class scientific advancements.

(With inputs from agencies.)

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