Breakthrough Breast Cancer Treatment by Pfizer and Arvinas Outshines Rival

Clinical trial results reveal an experimental treatment by Pfizer and Arvinas that delays breast cancer progression by over three months compared to AstraZeneca's Faslodex. The drug, vepdegestrant, targets ESR1 mutations and shows significant promise. Leerink Partners foresees significant market potential, projecting $576 million in peak sales by 2032.


Devdiscourse News Desk | Updated: 31-05-2025 17:32 IST | Created: 31-05-2025 17:32 IST
Breakthrough Breast Cancer Treatment by Pfizer and Arvinas Outshines Rival
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Recent clinical trial results have unveiled that an experimental treatment developed by Pfizer and Arvinas significantly delays the progression of breast cancer. Compared to AstraZeneca's Faslodex, this novel approach halted disease advancement by over three months, particularly in patients with specific gene mutations.

Presented at the American Society of Clinical Oncology's annual meeting, the findings indicate that the drug, vepdegestrant, recorded a remarkable increase in survival without disease progression. Although previous studies showed mixed results, the latest data highlights its effectiveness, earning Pfizer and Arvinas renewed hope in its market potential.

Analysis by Leerink Partners forecasts that vepdegestrant could generate $576 million in peak sales by 2032. This comes as Arvinas opts not to proceed with other planned late-stage studies, focusing on optimizing this promising treatment for advanced breast cancer patients.

(With inputs from agencies.)

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