Rethinking Inflammaging: A New Perspective on Ageing

A new study indicates that age-related inflammation, or 'inflammaging', may not be a universal aspect of ageing. Research on Indigenous groups suggests that chronic inflammation linked to age-related diseases in industrialized societies might stem from lifestyle differences. This challenges our understanding of ageing and suggests diverse approaches to healthcare.


Devdiscourse News Desk | York | Updated: 06-07-2025 09:26 IST | Created: 06-07-2025 09:26 IST
Rethinking Inflammaging: A New Perspective on Ageing
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A recent study published in Nature Aging challenges the long-held belief that inflammation inevitably increases with age, particularly in modern societies. This research examined Indigenous populations and found varying patterns of inflammation, which may redefine how we conceptualize ageing.

The study analyzed over 2,800 blood samples from populations in Italy, Singapore, the Bolivian Amazon, and the forests of Malaysia. It revealed that while industrialized societies displayed predictable inflammation associated with age-linked diseases, this was not observed in Indigenous groups.

The findings suggest that lifestyles typical of industrialized nations, characterized by high-calorie diets and less physical activity, may contribute to inflammaging. This research calls for further exploration of diverse populations to fully understand the intricacies of ageing.

(With inputs from agencies.)

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