Trio Wins Nobel Prize for Peripheral Immune Tolerance Breakthrough
Mary E Brunkow, Fred Ramsdell, and Shimon Sakaguchi have been awarded the Nobel Prize in medicine for their groundbreaking work on peripheral immune tolerance. This discovery plays a crucial role in preventing the immune system from attacking healthy tissues. The announcement marks the first of the 2025 Nobel Prize revelations.

- Country:
- Sweden
On Monday, Mary E Brunkow, Fred Ramsdell, and Shimon Sakaguchi were awarded the Nobel Prize in medicine for their pioneering discoveries related to peripheral immune tolerance. This crucial biological process prevents the immune system from mistakenly targeting the body's own tissues.
The announcement, made by the Nobel panel at Stockholm's Karolinska Institute, heralds the first of the 2025 Nobel Prize announcements. Last year's laureates, Americans Victor Ambros and Gary Ruvkun, were honored for their groundbreaking discovery of microRNA, tiny genetic components crucial in cellular functions.
The series of Nobel announcements will continue this week, with the physics prize set for Tuesday, followed by chemistry on Wednesday and literature on Thursday. The Nobel Peace Prize will be unveiled on Friday, and the Nobel Memorial Prize in economics will follow on October 13. The award ceremony is scheduled for December 10 to commemorate the passing of Alfred Nobel, the founder of the prizes.
(With inputs from agencies.)